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This is the first hour of a 2-hour season finale. A two episode entries have been created. The 10pm EST marker will mark to beginning of the second episode. A couple undergoes surgery. Derek and Meredith clinical trial has another patient. Izzie helps Alex. McSteamy hooks up with someone.

This is the second hour of a 2-hour season finale. A two episode entries have been created. The 10pm EST marker will mark to beginning of the second episode.

A couple undergoes surgery. Derek and Meredith clinical trial has another patient. Alex breaks down for the first time ever. Izzie offers a friend some help. McSteamy hooks up with someone. A new couple appears. Lexie gets something unexpectedly. George gets a second chance.

Dr. Wyatt refuses to let Meredith give up on therapy. Alex learns something else about Rebecca. The Chief wants Erica to perform a daring surgery. Cristina continues to act strange.

The clinical trial continues to make progress. The anti-McSteamy club creates new initiatives but that isn’t enough to stop one woman from spending time with him. Cristina is affected by Burke’s career developments.

Addison visits Seattle Grace because they need skills that only she has. Rebecca/Ava returns with news for Alex. Meredith and Derek’s clinical trial experiences one or two developments.