A young woman and her husband are rescued at sea en route from Cuba. House and the team take the couple on but in the process of running tests there becomes an obstacle. The woman’s condition begins to worsen and suddenly her heart stops . Meanwhile Foreman gets everything in order for his last day at Princeton-Plainsboro Teaching Hospital.
House has found his match. Nathan Harrison is a sixteen year old chess prodigy who is also very annoying. He gets admitted for severe head pain and behavioral problems. Nathan manages to get on everyone’s nerves. Nathan’s health begins to get worse and House is the only one that can handle his rude and annoying personality.
A nineteen year old girl named Addie is admitted to the hospital. Addie’s mouth started bleeding while she was at martial arts practice. House believe she has a infection that is causing her to bleed. Addie begins to get worse and House then suggests a treatment that means life or death.
A Leukemia patient who is fourteen years old is dying and her only hope is a bone marrow transplant from her younger brother. Her brother than becomes sick and the team must than try to save both children.
